CRISPR in the news - The first gene-edited babies have been born

CRISPR in the news - The first gene-edited babies have been born

The relatively-new genetic editing technology CRISPR is in the news this week.

The first report of gene-edited babies has come out, reported by a researcher in China who was trained and degreed at a university in the United States. Here’s a Slate article with more details if you haven’t heard about this breaking story yet. This Vox article gives a 101 intro to CRISPR.

CRISPR is a technology that uses a specially-designed protein with a short DNA segment attached to it to intentionally break a gene so that it doesn’t work and replace a region of DNA.

A DNA Surprise Five Decades in the Making - Part 2

THE STORY OF JUDEY AND GINNA: GINNA’S SIDE OF THE STORY:

Fishing has been something I’ve done nearly my whole life. It was a family affair; we’d pile in the boat and enjoy the relaxation and fun together. My dad and brother taught me to fish when I was three, and it is something I never stopped doing once I learned. Fishing is in my blood.

A DNA Surprise Five Decades in the Making - Part 1

A DNA Surprise Five Decades in the Making - Part 1

The Story of Judey and Ginna: Judey’s Side of the Story:

Birthdays have been bitter-sweet for me since I found out at age 21 that I was adopted as an infant. Since then -- and every year until last year -- the wish I made over my birthday candle was a desire to know who my biological family was.

How to test your DNA (even if you've had a stem cell transplant)

How to test your DNA (even if you've had a stem cell transplant)

What happens to DNA when someone has a stem cell transplant?

Some people have had a stem cell transplant using their own stem cells. This type of transplant does not have any impact on DNA and DNA test results. Organ transplants also do not appear to impact DNA results, even though the organ has come from a different person whose DNA differs from you.

Those who have had stem cell transplants in which they’ve received a stem cell donation from another person run into challenges when having a DNA test on blood or saliva. After transplant, the white blood cells circulating through the body contain the DNA of the stem cell donor because the blood-producing cells of the bone marrow have been replaced by the donor’s. Red blood cells are essentially sacks of hemoglobin and don’t contain DNA, so only white blood cells are the issue.

People who are discovering NPE are meeting up in-person for support and community

People who are discovering NPE are meeting up in-person for support and community

Guest Post by Rebekah Drumsta

Something magical is happening.  All across the world people are becoming friends, both online and at pre-arranged Meet and Greets.  They are making connections with others who’ve had an NPE (Not Parent Expected) event, just like them.

Starting a blog helped Stacey cope with her DNA Surprise

Starting a blog helped Stacey cope with her DNA Surprise

Blogging to Cope with My DNA Surprise: Stacey’s Story

A couple of weeks after my 41st birthday, my world as I knew it changed forever.  It’s a story we’ve now all heard: a DNA sample submitted to an ancestry website revealed unexpected biological data.  After asking my parents about it, they finally revealed that the man who raised me was not my biological father. I had so many questions - who was my biological father? Why did they lie? How could they keep it from me for so long?  Who knew?

GEDmatch & the Are Your Parents Related tool: What it means if you see a lot of blue

GEDmatch is a free website with tools that enable genealogists to use DNA and family trees to search for relatives. It has been in the news lately because it has recently been used to to identify criminal suspects. Tracing individuals based on their relatives DNA and family trees are only part of what GEDmatch allows DNA researchers to do. Other tools are available on GEDmatch, including one called "Are Your Parents Related?" (AYPR, for short). 

What DNA Testing Can't Tell You: a guest post on Family Tree's website

I recently wrote a post for Family Tree Magazine’s website called “What DNA Testing Can’t Tell You” in which I focus on things the test itself can’t tell you, like how you’ll react to your results or how to reach out to a surprise relative if you find one.

Making Your Existence Known to Bio Family - Should You or Shouldn't You?

Making Your Existence Known to Bio Family - Should You or Shouldn't You?

I had someone reach out to me a few months ago who was adopted and had reunited with his birth mom before she died after she sought him out. He never had interest in seeking out and reuniting with his birth father but accidentally matched to his (now deceased) bio father's family (an entire set of half-siblings) when doing an ancestry DNA test.

"What is NPE?" - A guest post by Steven King provides information and support for the surprise discovery in your family

WHAT IS NPE? BY STEVEN KING

A Non- Paternity Event (“NPE”) was originally the term used to explain the break in the paternal line for a male. In genetics and genealogy, the term signified that a person’s attributed father was not their biological father and that the family surname did not match the bloodline. Someone was presumed to be an individual’s father by the individual, the parents, their family or the healthcare practitioner involved. Today, the term is used more broadly to describe a break in the family line; for males or females with a misattributed father or mother. The acronym “NPE” is also used to describe individuals who learned they were conceived as a result of the event. Some also use the acronym to mean “Not Parent Expected.” 

DNA Surprise: Two sisters bond as they keep the secret of their shared DNA father

DNA Surprise: Two sisters bond as they keep the secret of their shared DNA father

I came to know Michelle and Eden when they joined the first secret support group I set up for people receiving DNA surprises for themselves or for someone’s DNA account they manage.

I asked the two of them to respond separately to some questions I had. The responses shed light to us as readers on how the same “DNA Surprise” event can be experienced differently.

You can read their detailed responses in the post here.