At home testing

DNA testing and family medical history: a short intro for genealogists

DNA testing and family medical history: a short intro for genealogists

Genealogists are a creative bunch, and I love to read about the information they discover and record about family. Some genealogists track down death certificates and record the official cause of death for ancestors. Others learn medical history from living relatives and write that down. I quietly applaud when I read about someone finding and saving medical information on ancestors and relatives like this!

As a genetic counselor and genealogist, family medical history will always be an important in my eyes. This information is difficult to retrieve once relatives pass away.  

MTHFR - a new article on Self.com lays out the facts

MTHFR - a new article on Self.com lays out the facts

There is a lot of misinformation spreading online about a gene all of us have called MTHFR. (We each have two copies it, actually: one from mom and one from dad.)

Self Magazine published an article this week specifically addressing the MTHFR gene and all the facts we know about it. It was written by Tara C. Smith, a person with a PhD in epidemiology. Epidemiology is the study of how different factors influence the health of people, and those with a PhD are trained to understand the outcome of studies at both the group level (large populations) and at the individual level (YOU!).

I read this article yesterday and feel like it is the BEST ARTICLE to date on MTHFR. It will be accessible to most readers, no matter your level of knowledge about DNA or genetics research.

To Birth Wives…there is growing support for you if you’re the wife of husbands in reunion with a daughter newly-found from DNA Testing

To Birth Wives…there is growing support for you if you’re the wife of husbands in reunion with a daughter newly-found from DNA Testing

One by one, women have begun to reach out to me. They describe a similar scenario.

Their husbands were unaware they had fathered a child in the past (typically, it's a daughter).

That child is now an adult.

Consumer DNA testing helped reunite the adult child with their father.

These situations involve a lot of emotions for everyone, including the adult child, the father, his wife/significant other, and other children in the family.

A brief note about the diabetes risk report from 23andMe

23andMe released a new health report this week, and it's quite a bit different from the other types of reports they've released in the past.

Most conditions that affect people (like type 2 diabetes) are complex in origin, meaning that even if it's "genetic," it's not necessarily easily-tested by DNA. This is due to reasons such as polygenic factors being influenced by environmental factors (diet, smoking, exercise, etc.). Polygenic refers to the fact that there can be dozens - if not hundreds or THOUSANDS - of genetic factors involved, each one having only a tiny impact on overall risk.

This is what you'll eventually see if you keep scrolling down your 23andMe report, and it's important to read and understand these things before you take anything away from your diabetes risk as reported by 23andMe. It’s important to know what a DNA test can’t tell you, as much as what it can.

Here’s the list of limitations you’ll see if you keep scrolling down your 23andMe report.

Here’s the list of limitations you’ll see if you keep scrolling down your 23andMe report.

Interested in reading more about this topic?

  • This article in MIT Technology Review brings some good points to the discussion.

  • This article by Jeanette McCarthy on Precision Medicine Advisors reviews polygenic risk scores, including a section on why they are controversial and not everyone agrees they are ready for prime time.

  • This article on the International Society of Genetic Genealogy wiki gives a good introduction to polygenic risks scores as well and is written by a PRS researcher.

If you are looking for a licensed and certified genetic counselor’s help in understanding your report, reach out or schedule with me. I’ll be happy to go through it and answer your questions!

“I am thankful that she told me the truth when I asked” - Christa’s Story of a DNA Surprise

“I am thankful that she told me the truth when I asked” - Christa’s Story of a DNA Surprise

The recorded re-telling of a painful and emotional experience of uncovering a DNA surprise is helpful for others to read. It supports and validates others who are going through the same thing, and it provides insight for the friends, family, and professionals who will be there alongside a person on their journey following the unexpected discovery.

An important point that my next guest blogger, Christa, makes is that receiving the truth from her mother rather than denial held so much value to her. She was so grateful that her mom ‘came clean’ straight away when she came to her with the discovery that the father she had grown up believing was her biological father was not.

Brianne Kirkpatrick Quoted in WebMD Magazine Articles on At Home DNA Testing

Brianne Kirkpatrick Quoted in WebMD Magazine Articles on At Home DNA Testing

I recently spoke with Sonya Collins who writes for WebMD Magazine. I shared my thoughts and advice on at home DNA tests based on years of both personal and professional experience, and I was pleased to see TWO articles come from it!

Please read, especially the second article! It will equip you to be a savvy chooser of a DNA tests you might purchase online and you can find more detailed advice than what made it into the article HERE.